Monday, 18 January 2016

New Members, Lineage II - B78262 & 446153

Two sets of new results were recently posted to the project (on January 16th), both of which are matches to those in Lineage II (the North Tipperary Gleeson's).

Member B78262
The first set are those of new member B78262 and he has tested out to 67 markers. His ancestry is from Ireland and his MDKA is Peter Gleeson born c1841 in Bruree, Co. Limerick and died in 1901 in Chicago. We hope to have his Gleeson pedigree up on the Patriarch Page of the website shortly and we are awaiting some additional information about his ancestry, including the family nickname (if known). I will update this post in due course to reflect this new information.

Many of you in Lineage II will have B78262 as a match among your list of matches, but some of you will not (if the Genetic Distance between you and him is greater than 4 mismatches out of 37 markers ... or 7/67, or 10/111). However, as Admins, Judy and I can see how closely each member is related to everyone else, including those beyond the 4/37 level. And so, below is the GD of B78262 to everyone in the group: 

You will see that he has a GD of 4/37 or less to 8 of the Lineage II members, 5/37 to 7 of them and 6/37 to 1. These last 8 members of Lineage II will not show up as a match to B78262. Interestingly, he matches all project members who have tested higher than 37 markers. (Note: n/a means not applicable, in other words you can only compare 37 marker data with 37, and 67 with 67, and 111 with 111. You cannot compare 37 with 111, for example).

Based on these values for Genetic Distance, it would appear that B78262 is most closely related to members 60393 & 411177. But a closer examination of the nature of the mutations and the markers in which they occur, suggests that he is more closely related to 60393.

TMRCA calculations place the common ancestor between B78262 and 60393 at about 11 generations back (90% range 5-20 generations) which gives a crude birth year of about 1630 (range 1360-1800). This also places him as an offshoot of Branch 2 in the current Mutation History Tree. And therefore other close cousins include 338070 and N74958 with corresponding TMRCA's of 13 generations back (90% range 6-23) and 15 (90% range 7-24+).

Member 446153
The second set of results belong to new member 446153. He has tested out to 37 markers and also has Irish ancestry. His MDKA is Denis GLEESON born c1844 Silvermines, died 1875 Bendigo, Victoria, Australia. We will post his pedigree shortly on the Patriarch's Page but here it is for information (note that Denis' father may have been Jeremiah):
  1. Denis GLEESON b. c1844 Silvermines, Co. Tipperary, d. 14 May 1875, Bendigo, VIC, Australia, m. Ann GRACE 15 Aug 1865, Silvermines, Co Tipperary.
  2. Jeremiah GLEESON b. 7 Feb 1870, Preston Vale (Bendigo) VIC, Australia, d. 2 Dec 1929, Mayfield NSW, Australia, m. Alice Ada BENNETT, 19 AUG 1899, Newcastle NSW, Australia.
  3. Gordon Charles GLEESON b 19 Mar 1902, Merewether NSW Australia, m. Daisy BRAMLEY, 10 Dec 1932, Mayfield NSW, Australia.
  4. Member 446153
At first glance, 446153 does not match anyone in the Gleason/Gleeson DNA Project. He only has 2 matches at the 37 marker level and neither of them are a Gleeson - one is a Hamilton, the other a McLachlan. However, this latter match gives us a very big clue ... Mr McLachlan's terminal SNP is Z16438 and this is an "upstream SNP" to those in Lineage II. And on closer inspection, 446153 does in fact match EVERYONE in Lineage II. And this means that his particular Gleeson branch is genetically related to the North Tipperary Gleeson’s.

The reason why none of the Lineage II Gleeson’s turn up on his matches page is that the cutoff for declaring a match is 4/37 (i.e. 4 mismatches out of 37 markers, also know as a Genetic Distance or GD of 4/37) and none of the Lineage II Gleeson's have a GD compared to him of 4/37 or less. Most people within the group are not exact matches to each other but rather differ by a few mutations. These are expressed as genetic distance - an exact match would be 0/37 or 0/67 for example and a difference of 4 would be 4/37. You can read more about it here ...

However, as Admins, Judy and I can see how closely each member is related to everyone else, including those beyond the 4/37 level. And so, below is the GD between 446153 and everyone else in the Lineage II group. You will see from the table below, that most of his mismatches are 5/37, and therefore just miss the cut-off for being declared as a “match” to him.

So, 446153 is a match to everyone in Lineage II of the Gleeson DNA Project, confirming that his Gleeson genetic origins are North Tipperary as indicated by his documentary evidence. 

There are 16 other people in Lineage II so far and new people are joining all the time. Some (like 446153) have tested to 37 markers, others have tested to 67 markers, and others to 111 markers. The n/a (not applicable) in the table above is because he has only tested to the 37 marker level and therefore we cannot compare his data to other members’ data above this level. I suspect that if he did test to 67 or 111 markers, he would find that a lot of people in Lineage II would then turn up in his list of matches (i.e. they would then fall within the thresholds for declaring a match, which would be up to 7/67, and up to 10/111 respectively).

His closest matches are the first 7 people in the table above (all with a GD of 5/37). I will have to take a close look at our current Mutation History Tree to see where he most likely fits within its current branching pattern (and therefore who in actuality is his closest relative). I will update this post in due course with that additional information.

Further results
Several additional results are expected in the next few weeks. Once the rest of the new results come in, they will all be added to the Lineage II Mutation History Tree. The updated tree will be the subject of a future post.

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